Entity Central Index Key
Document And Entity Information [Abstract]
Document And Entity Information [Abstract]
Document Type
Document Type
Amendment Flag
Amendment Flag
Document Period End Date
Document Period End Date
Document Fiscal Year Focus
Document Fiscal Year Focus
Document Fiscal Period Focus
Document Fiscal Period Focus
Trading Symbol
Trading Symbol
Entity Registrant Name
Entity Registrant Name
Entity Central Index Key
Current Fiscal Year End Date
Current Fiscal Year End Date
Entity Well-known Seasoned Issuer
Entity Well Known Seasoned Issuer
Entity Current Reporting Status
Entity Current Reporting Status
Entity Voluntary Filers
Entity Voluntary Filers
Entity Filer Category
Entity Filer Category
Entity Small Business
Entity Small Business
Entity Emerging Growth Company
Entity Emerging Growth Company
Entity Shell Company
Entity Shell Company
Entity Common Stock, Shares Outstanding
Entity Common Stock Shares Outstanding
Entity Public Float
Entity Public Float
The total amount due to the entity within one year of the balance sheet date (or one operating cycle, if longer) from outside sources, including amount of asset related to consideration paid in advance for costs that provide economic benefits within a future period of one year or the normal operating cycle, if longer. as well as trade accounts receivable, notes and loans receivable.
Statement Of Financial Position [Abstract]
Assets
Assets [Abstract]
Current assets:
Assets Current [Abstract]
Cash and cash equivalents
Cash And Cash Equivalents At Carrying Value
Restricted cash
Restricted Cash And Cash Equivalents At Carrying Value
Short-term investments
Short Term Investments
Accounts receivable, net
Accounts Receivable Net Current
Prepaid expenses and other current assets
Prepaid Expenses And Other Receivables
Intangible asset held for sale
Business Combination Recognized Identifiable Assets Acquired And Liabilities Assumed Intangible Assets Other Than Goodwill
Total current assets
Assets Current
Property and equipment, net
Property Plant And Equipment Net
Equity method investment
Equity Method Investments
Non-current restricted cash
Restricted Cash Noncurrent
Total assets
Assets
Liabilities and shareholders’ equity
Liabilities And Stockholders Equity [Abstract]
Current liabilities:
Liabilities Current [Abstract]
Accounts payable
Accounts Payable Current
Accrued liabilities
Accrued Liabilities Current
Deferred revenue
Deferred Revenue Current
Total current liabilities
Liabilities Current
Deferred revenue, net of current portion
Deferred Revenue Noncurrent
Long-term debt
Long Term Debt Noncurrent
Deferred rent
Deferred Rent Credit Noncurrent
Total liabilities
Liabilities
Commitments and contingencies (Note 13)
Commitments And Contingencies
Shareholders’ equity:
Stockholders Equity [Abstract]
Ordinary shares: 30,000 shares authorized, 10,762 issued, 10,719 outstanding and 43 held in treasury at December 31, 2018; NIS 0.07 par value; 30,000 shares authorized, 10,699 issued, 10,656 outstanding and 43 held in treasury at December 31, 2017;
Common Stock Value
Additional paid-in capital
Additional Paid In Capital
Accumulated other comprehensive loss
Accumulated Other Comprehensive Income Loss Net Of Tax
Accumulated deficit
Retained Earnings Accumulated Deficit
Total shareholders’ equity
Stockholders Equity
Total liabilities and shareholders’ equity
Liabilities And Stockholders Equity
Common stock, par value
Common Stock Par Or Stated Value Per Share
Common stock, shares authorized
Common Stock Shares Authorized
Treasury shares
Treasury Stock Common Shares
Common stock, shares issued
Common Stock Shares Issued
Common stock, shares outstanding
Common Stock Shares Outstanding
Statement Of Income And Comprehensive Income [Abstract]
Collaboration revenue
Revenues
Operating expenses:
Operating Expenses [Abstract]
Research and development, net
Research And Development Expense
General and administrative
General And Administrative Expense
Total operating expenses
Operating Expenses
Net loss from operations
Operating Income Loss
Loss from equity method investment
Income Loss From Equity Method Investments
Finance income (expense), net
Other Nonoperating Income Expense
Net loss before taxes
Income Loss From Continuing Operations Before Income Taxes Extraordinary Items Noncontrolling Interest
Income tax expense
Income Tax Expense Benefit
Net loss
Net Income Loss
Net loss per share, basic and diluted
Earnings Per Share Basic And Diluted
Weighted-average shares outstanding, basic and diluted
Weighted Average Number Of Share Outstanding Basic And Diluted
Comprehensive loss:
Comprehensive Income Net Of Tax [Abstract]
Net loss
Unrealized gain (loss) on short-term investments
Other Comprehensive Income Unrealized Holding Gain Loss On Securities Arising During Period Net Of Tax
Comprehensive loss
Comprehensive Income Net Of Tax
Stock issued during period, shares, warrants exercised.
Stock issued during period value, warrants exercised.
Stock issued during period, shares, conversion of debt securities.
Stock issued during period, value, conversion of debt securities.
Adjustments to additional paid-in capital, beneficial conversion expense from notes.
Stock issued during period, shares, merger net of refund for fractional shares.
Stock issued during period, value, merger, net of refund for fractional shares.
Statement Of Stockholders Equity [Abstract]
Statement [Table]
Statement [Table]
Equity Components
Statement Equity Components [Axis]
Equity Component
Equity Component [Domain]
Ordinary Shares [Member]
Common Stock [Member]
Additional Paid-In Capital [Member]
Additional Paid In Capital [Member]
Accumulated Other Comprehensive Loss [Member]
Accumulated Other Comprehensive Income [Member]
Accumulated Deficit [Member]
Retained Earnings [Member]
Class of Stock
Statement Class Of Stock [Axis]
Class of Stock
Class Of Stock [Domain]
Series seed preferred stock.
Series Seed Preferred Stock [Member]
Series Seed Preferred Stock [Member]
Series A Preferred Stock
Series A Preferred Stock [Member]
Statement [Line Items]
Statement [Line Items]
Balance
Balance (in shares)
Shares Outstanding
Share-based compensation
Adjustments To Additional Paid In Capital Sharebased Compensation Requisite Service Period Recognition Value
Issuance of common shares upon exercise of share options
Stock Issued During Period Value Stock Options Exercised
Issuance of common shares upon exercise of share options (in shares)
Stock Issued During Period Shares Stock Options Exercised
Issuance of shares upon exercise of warrants
Stock Issued During Period Value Warrants Exercised
Issuance of shares upon exercise of warrants (in shares)
Stock Issued During Period Shares Warrants Exercised
Issuance of shares upon conversion of notes
Stock Issued During Period Value Conversion Of Debt Securities
Issuance of shares upon conversion of notes (in shares)
Stock Issued During Period Shares Conversion Of Debt Securities
Conversion of preferred shares to ordinary shares
Stock Issued During Period Value Conversion Of Convertible Securities
Conversion of Preferred Shares to ordinary shares (in shares)
Stock Issued During Period Shares Conversion Of Convertible Securities
Beneficial conversion expense from notes
Adjustments To Additional Paid In Capital Beneficial Conversion Expense From Notes
Issuance of shares in connection with merger, net
Stock Issued During Period Value Merger Net Of Refund For Fractional Shares
Issuance of shares in connection with merger, net (in shares)
Stock Issued During Period Shares Merger Net Of Refund For Fractional Shares
Balance
Balance (in shares)
Non Cash Interest Expenses.
Debt conversion expense.
Sale of intangible assets for equity method investment.
Release of repurchase liability for restricted shares.
Statement Of Cash Flows [Abstract]
OPERATING ACTIVITIES:
Net Cash Provided By Used In Operating Activities [Abstract]
Adjustments to reconcile net loss to net cash used in operating activities:
Adjustments To Reconcile Net Income Loss To Cash Provided By Used In Operating Activities [Abstract]
Depreciation and amortization
Depreciation And Amortization
Share-based compensation expense
Share Based Compensation
Loss from equity method investment
Non cash interest expenses
Non Cash Interest Expenses
Debt conversion expense
Debt Conversion Expense
Changes in operating assets and liabilities:
Increase Decrease In Operating Capital [Abstract]
Accounts receivable
Increase Decrease In Accounts Receivable
Prepaid expenses and other assets
Increase Decrease In Prepaid Deferred Expense And Other Assets
Accounts payable
Increase Decrease In Accounts Payable
Accrued liabilities
Increase Decrease In Accrued Liabilities
Deferred revenue
Increase Decrease In Deferred Revenue
Net cash used in operating activities
Net Cash Provided By Used In Operating Activities
INVESTING ACTIVITIES:
Net Cash Provided By Used In Investing Activities [Abstract]
Acquisition of property and equipment
Payments To Acquire Property Plant And Equipment
Purchases of short-term investments
Payments To Acquire Short Term Investments
Proceeds from sale of equipment
Proceeds From Sale Of Property Plant And Equipment
Proceeds from maturities of short-term investments
Proceeds From Maturities Prepayments And Calls Of Shortterm Investments
Net cash provided by investing activities
Net Cash Provided By Used In Investing Activities
FINANCING ACTIVITIES:
Net Cash Provided By Used In Financing Activities [Abstract]
Proceeds from long-term debt, net of debt issuance costs
Proceeds From Issuance Of Long Term Debt
Proceeds from exercise of stock options
Proceeds From Stock Options Exercised
Proceeds from issuance of convertible promissory notes
Proceeds From Convertible Debt
Proceeds from exercise of warrants
Proceeds From Warrant Exercises
Net cash received in the issuance of shares for the net assets of Alcobra Ltd.
Proceeds From Issuance Of Common Stock
Net cash provided by financing activities
Net Cash Provided By Used In Financing Activities
NET INCREASE IN CASH, CASH EQUIVALENTS AND RESTRICTED CASH
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Period Increase Decrease Including Exchange Rate Effect
Cash, cash equivalents and restricted cash at beginning of year
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents
Cash, cash equivalents and restricted cash at end of year
Supplemental disclosure of cash flow information:
Supplemental Cash Flow Information [Abstract]
Cash paid for interest
Interest Paid Net
Cash paid for income taxes
Income Taxes Paid
Sale of intangible assets for equity method investment
Sale Of Intangible Assets For Equity Method Investment
Purchase of property and equipment in accounts payable
Capital Expenditures Incurred But Not Yet Paid
Release of repurchase liability for restricted shares
Release Of Repurchase Liability For Restricted Shares
Conversion of notes to ordinary shares
Debt Conversion Converted Instrument Amount1
Fair value of assets acquired, excluding cash, cash equivalents and restricted cash
Noncash Or Part Noncash Acquisition Value Of Assets Acquired1
Less: liabilities assumed
Noncash Or Part Noncash Acquisition Value Of Liabilities Assumed1
Net assets acquired, excluding cash, cash equivalents and restricted cash
Noncash Or Part Noncash Acquisition Net Nonmonetary Assets Acquired Liabilities Assumed1
Organization Consolidation And Presentation Of Financial Statements [Abstract]
Organization
Business Description And Accounting Policies [Text Block]
Accounting Policies [Abstract]
Summary of Significant Accounting Policies
Significant Accounting Policies [Text Block]
Collaboration agreements.
Collaboration Agreements [Abstract]
Collaboration Revenue
Collaborative Arrangement Disclosure [Text Block]
Investments Debt And Equity Securities [Abstract]
Short-term Investments
Investments In Debt And Marketable Equity Securities And Certain Trading Assets Disclosure [Text Block]
Fair Value Disclosures [Abstract]
Fair Value Measurements
Fair Value Disclosures [Text Block]
Business Combinations [Abstract]
Reverse Merger with Alcobra Ltd.
Business Combination Disclosure [Text Block]
Balance Sheet Related Disclosures [Abstract]
Balance Sheet Details
Supplemental Balance Sheet Disclosures [Text Block]
Property Plant And Equipment [Abstract]
Property and Equipment, Net
Property Plant And Equipment Disclosure [Text Block]
Debt Disclosure [Abstract]
Debt
Debt Disclosure [Text Block]
Stockholders Equity Note [Abstract]
Shareholders’ Equity
Stockholders Equity Note Disclosure [Text Block]
Disclosure Of Compensation Related Costs Sharebased Payments [Abstract]
Share-Based Compensation
Disclosure Of Compensation Related Costs Share Based Payments [Text Block]
Income Tax Disclosure [Abstract]
Income Taxes
Income Tax Disclosure [Text Block]
Commitments And Contingencies Disclosure [Abstract]
Commitments and Contingencies
Commitments And Contingencies Disclosure [Text Block]
Related Party Transactions [Abstract]
Related Party Transactions
Related Party Transactions Disclosure [Text Block]
Loss Contingency Information About Litigation Matters [Abstract]
Litigation
Loss Contingency Disclosures
Subsequent Events [Abstract]
Subsequent Events
Subsequent Events [Text Block]
Basis of Presentation and Principles of Consolidation
Consolidation Policy [Text Block]
Segment Information
Segment Reporting Policy Policy [Text Block]
Cash and Cash Equivalents
Cash And Cash Equivalents Policy [Text Block]
Restricted Cash
Cash And Cash Equivalents Restricted Cash And Cash Equivalents Policy
Short-term bank deposits.
Short-term Bank Deposits
Short Term Bank Deposits Policy Policy [Text Block]
Disclosure of accounting policy for short-term investments.
Short-term Investments
Short Term Investments Policy [Text Block]
Fair Value Measurements
Fair Value Measurement Policy Policy [Text Block]
Accounts Receivable
Receivables Policy [Text Block]
Concentration of Credit Risk and Significant Customers
Concentration Risk Credit Risk
Intangible Assets Held for Sale and Equity Method Investment
Impairment Or Disposal Of Long Lived Assets Including Intangible Assets Policy Policy [Text Block]
Property and Equipment, net
Property Plant And Equipment Policy [Text Block]
Comprehensive Income/Loss
Comprehensive Income Policy Policy [Text Block]
Revenue Recognition
Revenue Recognition Policy [Text Block]
Research and Development Costs, net
Research And Development Expense Policy
Share-Based Compensation
Share Based Compensation Option And Incentive Plans Policy
Ordinary shares valuation.
Ordinary Shares Valuation
Ordinary Shares Valuation Policy [Text Block]
Income Tax Expense
Income Tax Policy [Text Block]
Net Loss per Share
Earnings Per Share Policy [Text Block]
Recently Issued Accounting Pronouncements
New Accounting Pronouncements Policy Policy [Text Block]
Schedule of Cash and Cash Equivalents and Restricted Cash
Schedule Of Cash And Cash Equivalents Table [Text Block]
Schedule of collaboration revenue.
Summary of Collaboration Revenue
Schedule Of Collaboration Revenue Table [Text Block]
Summary of Short-term Investments
Debt Securities Available For Sale Table [Text Block]
Schedule of Financial Assets Measured at Fair Value on a Recurring Basis
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis Table [Text Block]
Summary of Fair Value of Assets and Liabilities Acquired
Schedule Of Recognized Identified Assets Acquired And Liabilities Assumed Table [Text Block]
Schedule of Accrued Liabilities
Schedule Of Accrued Liabilities Table [Text Block]
Summary of Components of Property and Equipment
Property Plant And Equipment [Text Block]
Schedule of Maturities of Long-term Debt
Schedule Of Maturities Of Long Term Debt Table [Text Block]
Schedule of Weighted Average Assumptions Used in Black -Scholes Valuation Model
Schedule Of Share Based Payment Award Stock Options Valuation Assumptions Table [Text Block]
Summary of Share Option Activity
Schedule Of Share Based Compensation Stock Options Activity Table [Text Block]
Schedule of Share-based Compensation Expenses
Schedule Of Compensation Cost For Share Based Payment Arrangements Allocation Of Share Based Compensation Costs By Plan Table [Text Block]
Summary of Reconciliation of Loss Before Income Taxes for Domestic and Foreign Locations
Schedule Of Income Before Income Tax Domestic And Foreign Table [Text Block]
Summary of Reconciliation of Income Tax Expense
Schedule Of Unrecognized Tax Benefits Roll Forward Table [Text Block]
Significant Components of Deferred Income Taxes
Schedule Of Deferred Tax Assets And Liabilities Table [Text Block]
Reconciliation of Federal Statutory Income Tax Rate to Company's Effective Income Tax Rate
Schedule Of Effective Income Tax Rate Reconciliation Table [Text Block]
Schedule of Future Minimum Payments Under Leases and Lease Commitments
Schedule Of Future Minimum Rental Payments For Operating Leases Table [Text Block]
Organization and significant accounting policies line items.
Organization and significant accounting policies.
Organization And Significant Accounting Policies [Table]
Organization And Significant Accounting Policies [Table]
Business Acquisition
Business Acquisition [Axis]
Business Acquisition, Acquiree
Business Acquisition Acquiree [Domain]
Alcobra Limited.
Alocobra Limited [Member]
Alcobra Limited [Member]
Type of Arrangement and Non-arrangement Transactions
Type Of Arrangement [Axis]
Arrangements and Non-arrangement Transactions
Arrangements And Nonarrangement Transactions [Member]
Loan and security agreement.
Loan and Security Agreement [Member]
Loan And Security Agreement [Member]
Sales agreement.
Sales Agreement [Member]
Sales Agreement [Member]
Legal Entity
Legal Entity [Axis]
Entity
Entity [Domain]
Leerink Partners LLC.
Leerink Partners LLC [Member]
Leerink Partners L L C [Member]
Range
Range [Axis]
Range
Range [Member]
Maximum [Member]
Maximum [Member]
Minimum [Member]
Minimum [Member]
Long-term Debt, Type
Longterm Debt Type [Axis]
Long-term Debt, Type
Longterm Debt Type [Domain]
Term loan.
Term Loan [Member]
Term Loan [Member]
Organization And Significant Accounting Policies [Line Items]
Organization And Significant Accounting Policies [Line Items]
Business merger date
Business Acquisition Effective Date Of Acquisition1
Stock issued during period, shares, acquisitions
Stock Issued During Period Shares Acquisitions
Par value per share
Reverse split of ordinary shares
Stockholders Equity Reverse Stock Split
Reverse split of ordinary shares, ratio
Stockholders Equity Note Stock Split Conversion Ratio1
Aggregate amount of ordinary shares sold.
Gross proceeds from issuance of long-term debt.
Gross proceeds from long-term debt agreement
Gross Proceeds From Issuance Of Long Term Debt
Aggregate amount of ordinary shares sold
Aggregate Amount Of Ordinary Shares Sold
Summary of significant accounting policy.
Schedule of summary of significant accounting policies.
Schedule Of Summary Of Significant Accounting Policies [Table]
Schedule Of Summary Of Significant Accounting Policies [Table]
Concentration Risk Type
Concentration Risk By Type [Axis]
Concentration Risk Type
Concentration Risk Type [Domain]
Credit Risk [Member]
Credit Concentration Risk [Member]
Concentration Risk Benchmark
Concentration Risk By Benchmark [Axis]
Concentration Risk Benchmark
Concentration Risk Benchmark [Domain]
Accounts Receivable [Member]
Accounts Receivable [Member]
Revenue [Member]
Sales Revenue Net [Member]
Vesting
Vesting [Axis]
Vesting
Vesting [Domain]
First Year Anniversary of the Grant [Member]
Share Based Compensation Award Tranche One [Member]
Title of Individual
Title Of Individual [Axis]
Relationship to Entity
Title Of Individual With Relationship To Entity [Domain]
Non-employees.
Non-employee [Member]
Nonemployees [Member]
Adjustments for New Accounting Pronouncements
Adjustments For New Accounting Pronouncements [Axis]
Type of Adoption
Type Of Adoption [Member]
ASU 2016-02 [Member]
Accounting Standards Update201602 [Member]
Summary Of Significant Accounting Policy [Line Items]
Summary Of Significant Accounting Policy [Line Items]
Number of Operating Segments
Number Of Operating Segments
Lease expiration year.
Lease expiration year
Lease Expiration Year
Restricted cash, current
Restricted Cash Current
Available-for-sale securities
Available For Sale Securities Debt Securities Current
Allowance for Doubtful Accounts Receivable
Allowance For Doubtful Accounts Receivable
Concentration risk number of customer.
Number of customers
Concentration Risk Number Of Customer
Concentration risk, percentage
Concentration Risk Percentage1
Equity method ownership percentage
Equity Method Investment Ownership Percentage
Share of losses for investee
Property and equipment, useful lives
Property Plant And Equipment Useful Life
Impairment losses
Goodwill Impairment Loss
Share options expiration period
Sharebased Compensation Arrangement By Sharebased Payment Award Expiration Period
Vesting period
Share Based Compensation Arrangement By Share Based Payment Award Award Vesting Period1
Vesting percentage
Sharebased Compensation Arrangement By Sharebased Payment Award Award Vesting Rights Percentage
Vesting description
Share Based Compensation Arrangement By Share Based Payment Award Award Vesting Rights
Share-based awards granted
Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Gross
Restricted cash
Non-current Restricted cash
Total cash, cash equivalents and restricted cash shown in the statement of cash flows
Tax cuts and jobs act of 2017 accounting complete date.
Tax Cuts and Jobs Act, accounting complete, date
Tax Cuts And Jobs Act Of2017 Accounting Complete Date
Accounting requirements
Income Tax Reconciliation Other Reconciling Items
Tax cuts and jobs act of 2017 complete accounting change in tax rate remeasurement of deferred tax assets.
Tax cuts and jobs act of 2017, remeasurement of deferred tax assets
Tax Cuts And Jobs Act Of2017 Complete Accounting Change In Tax Rate Remeasurement Of Deferred Tax Assets
Dividends declared
Dividends Common Stock
Dividends paid
Payments Of Dividends Common Stock
Incremental borrowing rate.
Derecognition of deferred rent.
Operating lease assets
Operating Lease Right Of Use Asset
Operating lease liabilities
Operating Lease Liability
Incremental borrowing rate
Incremental Borrowing Rate
Derecognition of deferred rent
Derecognition Of Deferred Rent
Schedule Of Collaborative Arrangements And Noncollaborative Arrangement Transactions [Table]
Schedule Of Collaborative Arrangements And Noncollaborative Arrangement Transactions [Table]
Research Collaboration and Exclusive License Agreement.
Research Collaboration and Exclusive License Agreement [Member]
Research Collaboration And Exclusive License Agreement [Member]
Geographical
Statement Geographical [Axis]
Geographical
Segment Geographical [Domain]
Foreign countries.
Foreign Countries [Member]
Foreign Countries [Member]
Counterparty Name
Counterparty Name [Axis]
Counterparty Name
Repurchase Agreement Counterparty Name [Domain]
Collaboration Partner Janssen two thousand fifteen agreements.
Collaboration Partner Janssen 2015 Agreements [Member]
Collaboration Partner Janssen Two Thousand Fifteen Agreements [Member]
Collaboration Partner Janssen Two Thousand Seventeen Agreements.
Collaboration Partner Janssen 2017 Agreements [Member]
Collaboration Partner Janssen Two Thousand Seventeen Agreements [Member]
Collaboration partner ultragenyx.
Collaboration Partner – Ultragenyx [Member]
Collaboration Partner Ultragenyx [Member]
Deferred Revenue Arrangement Type
Deferred Revenue Arrangement Type [Axis]
Timing of Transfer of Good or Service
Timing Of Transfer Of Good Or Service [Domain]
Up-Front Fee [Member]
Up Front Payment Arrangement [Member]
Collaboration partner Takeda.
Collaboration Partner – Takeda [Member]
Collaboration Partner Takeda [Member]
Collaboration Partner Cure Vac entered into Co-Development Agreement.
Collaboration Partner – CureVac Entered into Co-Development Agreement [Member]
Collaboration Partner Cure Vac Entered Into Co Development Agreement [Member]
mRNA technology.
mRNA Technology [Member]
M R N A Technology [Member]
Collaboration partner cureVac.
Collaboration Partner – CureVac [Member]
Collaboration Partner Cure Vac [Member]
Subsequent Event Type
Subsequent Event Type [Axis]
Subsequent Event Type
Subsequent Event Type [Domain]
Subsequent Event [Member]
Subsequent Event [Member]
Research and exclusive license agreement.
Research and Exclusive License Agreement [Member]
Research And Exclusive License Agreement [Member]
Research collaboration and license agreement.
Research Collaboration and License Agreement [Member]
Research Collaboration And License Agreement [Member]
Synthetic Genomics, Inc.
Synthetic Genomics, Inc [Member]
Synthetic Genomics Inc [Member]
Product and Service
Product Or Service [Axis]
Product and Service
Products And Services [Domain]
LUNAR product.
LUNAR Product [Member]
L U N A R Product [Member]
Non-LUNAR product.
Non-LUNAR Product [Member]
Non L U N A R Product [Member]
Related Party
Related Party Transactions By Related Party [Axis]
Related Party
Related Party [Domain]
Providence Therapeutics Incorporation.
Providence Therapeutics, Inc [Member]
Providence Therapeutics Incorporation [Member]
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Collaboration Partner Janssen.
Collaboration Partner – Janssen [Member]
Collaboration Partner Janssen [Member]
Other collaboration.
Other Collaboration [Member]
Other Collaboration [Member]
Upfront payment received.
Reimbursement revenues.
Option exercise revenue range per target.
Upfront fee received.
Collaborative arrangement research and development revenue recognized on amortization of upfront payment.
Revenue recognition potential milestone revenue recognized.
Number of collaboration agreements.
Number of collaboration agreements
Number Of Collaboration Agreements
Revenue earned and recognized upon amortization of the upfront payment
Collaborative Arrangement Research And Development Revenue Recognized On Amortization Of Upfront Payment
Labor and expense reimbursements revenue
Reimbursement Revenues
Upfront payment received
Upfront Payment Received
Revenue recognition potential milestone revenue recognized
Revenue Recognition Potential Milestone Revenue Recognized
Option exercise revenue range per target
Option Exercise Revenue Range Per Target
Upfront fee received
Upfront Fee Received
Deferred revenue
Deferred Revenue
Revenue recognition, milestone
Revenue Recognition Milestone Method Milestone
Royalty payment term description.
Royalty payment term description
Royalty Payment Term Description
Amortization period expected termination date.
Up-front fee deferred and recognized
Deferred Revenue Revenue Recognized1
Amortization period expected termination date.
Amortization Period Expected Termination Date
Revenue recognized as one time payment.
Revenue recognized as one time payment
Revenue Recognized As One Time Payment
Revenue recognition research activities period.
Revenue recognition research activities period
Revenue Recognition Research Activities Period
Research Funding Payments Received.
Regularly scheduled research funding payments
Research Funding Payments Received
Development and option agreement date.
Upfront license fees.
Upfront license fees
Upfront License Fees
Development and option agreement date
Development And Option Agreement Date
Percentage of global rights reassumed.
Collaborative Arrangement sharing percentage.
Collaboration agreement termination date.
Collaboration agreement termination date
Collaboration Agreement Termination Date
Percentage of global rights reassumed
Percentage Of Global Rights Reassumed
Percentage share of collaborative arrangement
Collaborative Arrangement Sharing Percentage
Percentage of cash payments received.
Percentage of consideration received.
Revenue related to amortization of upfront payment.
Labor reimbursement and sublicense revenue recognized.
Percentage of all cash payments received
Percentage Of Cash Payments Received
Percentage of consideration received
Percentage Of Consideration Received
Labor reimbursement and sublicense revenue recognized
Labor Reimbursement And Sublicense Revenue Recognized
Revenue related to amortization of upfront payment
Revenue Related To Amortization Of Upfront Payment
Percentage of short-term bank deposit weighted average interest rate during the period.
Schedule Of Available For Sale Securities [Table]
Schedule Of Available For Sale Securities [Table]
Cash and Cash Equivalents
Cash And Cash Equivalents [Axis]
Cash and Cash Equivalents
Restricted Cash And Cash Equivalents Cash And Cash Equivalents [Member]
Bank Deposits [Member]
Bank Time Deposits [Member]
Schedule Of Available For Sale Securities [Line Items]
Schedule Of Available For Sale Securities [Line Items]
Total amount short-term investments
Short Term Deposit Weighted Average Interest Rate
Short Term Deposit Weighted Average Interest Rate
Short-term investment
Financial Instrument
Financial Instrument [Axis]
Financial Instruments
Transfers And Servicing Of Financial Instruments Types Of Financial Instruments [Domain]
Corporate Debt Securities [Member]
Corporate Debt Securities [Member]
Investment Type
Investment Type [Axis]
Investments
Investment Type Categorization [Member]
Certificates of Deposit [Member]
Certificates Of Deposit [Member]
Amortized cost
Available For Sale Debt Securities Amortized Cost Basis
Gross unrealized gains
Available For Sale Debt Securities Accumulated Gross Unrealized Gain Before Tax
Gross unrealized losses
Available For Sale Debt Securities Accumulated Gross Unrealized Loss Before Tax
Fair value
Available For Sale Securities Debt Securities
Certificates of deposit fair value disclosure.
Corporate debt securities fair value disclosure.
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Table]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Table]
Measurement Frequency
Fair Value By Measurement Frequency [Axis]
Fair Value, Measurement Frequency
Fair Value Measurement Frequency [Domain]
Fair Value, Measurements, Recurring [Member]
Fair Value Measurements Recurring [Member]
Fair Value Hierarchy and NAV
Fair Value By Fair Value Hierarchy Level [Axis]
Fair Value Hierarchy and NAV
Fair Value Measurements Fair Value Hierarchy [Domain]
Fair Value, Inputs, Level 1 [Member]
Fair Value Inputs Level1 [Member]
Fair Value, Inputs, Level 2 [Member]
Fair Value Inputs Level2 [Member]
Fair Value, Inputs, Level 3 [Member]
Fair Value Inputs Level3 [Member]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items]
Assets Fair Value Disclosure [Abstract]
Assets Fair Value Disclosure [Abstract]
Cash equivalents
Cash And Cash Equivalents Fair Value Disclosure
Certificates of deposit
Certificates Of Deposit Fair Value Disclosure
Corporate debt securities
Corporate Debt Securities Fair Value Disclosure
Total financial assets
Assets Fair Value Disclosure
Business combination recognized identifiable assets acquired and liabilities assumed restricted cash.
Schedule Of Business Acquisitions By Acquisition [Table]
Schedule Of Business Acquisitions By Acquisition [Table]
Business Acquisition [Line Items]
Business Acquisition [Line Items]
Cash and cash equivalents
Business Combination Recognized Identifiable Assets Acquired And Liabilities Assumed Cash And Equivalents
Restricted cash
Business Combination Recognized Identifiable Assets Acquired And Liabilities Assumed Restricted Cash
Short-term investments
Business Combination Recognized Identifiable Assets Acquired And Liabilities Assumed Current Assets Marketable Securities
Prepaid and other assets
Business Combination Recognized Identifiable Assets Acquired And Liabilities Assumed Current Assets Prepaid Expense And Other Assets
Property, plant and equipment – held for sale
Business Combination Recognized Identifiable Assets Acquired And Liabilities Assumed Property Plant And Equipment
Total assets acquired
Business Combination Recognized Identifiable Assets Acquired And Liabilities Assumed Assets
Accounts payable and accrued expenses
Business Combination Recognized Identifiable Assets Acquired And Liabilities Assumed Current Liabilities Accounts Payable
Net assets acquired
Business Combination Recognized Identifiable Assets Acquired And Liabilities Assumed Net
Business combination charge to additional paid-in capital.
Amiservice.
Amiservice [Member]
Amiservice [Member]
Investment, Name
Schedule Of Equity Method Investment Equity Method Investee Name [Axis]
Investment, Name
Equity Method Investee Name [Domain]
Total fair value of consideration paid
Business Combination Consideration Transferred1
Shares outstanding as on merger date
Closing price as on merger date
Business Acquisition Share Price
Charge to additional paid-in capital
Business Combination Charge To Additional Paid In Capital
Payments for merger related costs
Payments For Merger Related Costs
Equity method investment, description
Equity Method Investment Description Of Principal Activities
Accrued Liabilities Current [Abstract]
Accrued compensation
Employee Related Liabilities Current
Refundable fees received
Customer Refund Liability Current
Other accrued liabilities
Other Accrued Liabilities Current
Total
Schedule Of Property Plant And Equipment [Table]
Schedule Of Property Plant And Equipment [Table]
Property, Plant and Equipment, Type
Property Plant And Equipment By Type [Axis]
Property, Plant and Equipment, Type
Property Plant And Equipment Type [Domain]
Research equipment [Member]
Equipment [Member]
Computer and software [Member]
Computer Equipment [Member]
Office equipment and furniture [Member]
Furniture And Fixtures [Member]
Leasehold improvements [Member]
Leasehold Improvements [Member]
Property Plant And Equipment [Line Items]
Property Plant And Equipment [Line Items]
Property and equipment, gross
Property Plant And Equipment Gross
Less accumulated depreciation and amortization
Accumulated Depreciation Depletion And Amortization Property Plant And Equipment
Property and equipment, net
Debt instrument Interest-only repayment period.
Debt instrument interest only repayment period extended.
Debt instrument amortization period.
Debt instrument amortization period for extended interest only period.
Debt Instrument [Table]
Debt Instrument [Table]
Western Alliance Bank.
Western Alliance Bank [Member]
Western Alliance Bank [Member]
Long-term Debt [Member]
Long Term Debt [Member]
Short-term Debt, Type
Short Term Debt Type [Axis]
Short-term Debt, Type
Short Term Debt Type [Domain]
Convertible Promissory Notes [Member]
Convertible Notes Payable [Member]
Debt Instrument [Line Items]
Debt Instrument [Line Items]
Loan maturity date
Debt Instrument Maturity Date
Interest of the prime rate plus
Debt Instrument Basis Spread On Variable Rate1
Loan interest payment terms
Debt Instrument Payment Terms
Loan interest-only payment period
Debt Instrument Interest Only Repayment Period
Loan interest-only payment period
Debt Instrument Interest Only Repayment Period Extended
Debt Instrument, amortization period
Debt Instrument Amortization Period
Debt Instrument, amortization period
Debt Instrument Amortization Period For Extended Interest Only Period
Warrant fee payable.
Loan orgination fee paid
Unamortized Loan Commitment And Origination Fees And Unamortized Discounts Or Premiums
Warrant fee payable
Warrant Fee Payable
Prepayment fee percentage.
Prepayment fee percentage after accepting new drug applications prior to maturity.
Fee payable upon repayment.
Percentage of fee liable on principal balance.
Prepayment fee percentage
Prepayment Fee Percentage
Prepayment fee percentage
Prepayment Fee Percentage After Accepting New Drug Applications Prior To Maturity
Percentage of fee liable on principal balance
Percentage Of Fee Liable On Principal Balance
Fee payable upon repayment
Fee Payable Upon Repayment
Percentage required to be maintained in deposit and investment account.
Debt instrument, collateral
Debt Instrument Collateral
Percentage required to be maintain in deposit and investment
Percentage Required To Be Maintained In Deposit And Investment Account
Debt instrument, collateral amount
Debt Instrument Collateral Amount
Available sale of equity securities
Available For Sale Securities Equity Securities Current
Outstanding long-term debt
Accretion of final payment
Debt Instrument Periodic Payment Terms Balloon Payment To Be Paid
Unamortized debt discount
Debt Instrument Unamortized Discount
2019
Long Term Debt Maturities Repayments Of Principal In Next Twelve Months
2020
Long Term Debt Maturities Repayments Of Principal In Year Two
2021
Long Term Debt Maturities Repayments Of Principal In Year Three
2021
Long Term Debt Maturities Repayments Of Principal In Year Four
Total
Long Term Debt
Accrued interest on promissory note.
Convertible promissory note, amount converted
Debt Conversion Original Debt Amount1
Accrued interest
Accrued Interest On Promissory Note
Common stock average conversion rate
Debt Instrument Convertible Conversion Price1
Recognized additional net expense for conversion
Induced Conversion Of Convertible Debt Expense
Interest expense related to long-term debt
Interest Expense Long Term Debt
Conversion of stock conversion ratio.
Schedule Of Stock By Class [Table]
Schedule Of Stock By Class [Table]
Sale of Stock
Subsidiary Sale Of Stock [Axis]
Sale of Stock
Sale Of Stock Name Of Transaction [Domain]
Arcturus Therapeutics Inc.
Arcturus Inc [Member]
Arcturus Inc [Member]
Vested After Obtaining Suitable siRNA License [Member]
Vested After in Vivo Proof-of-concept Achieved [Member]
Share Based Compensation Award Tranche Two [Member]
Vested After IND Application Completed [Member]
Share Based Compensation Award Tranche Three [Member]
Share based compensation award tranche four.
Vested After in Human Efficacy Achieved [Member]
Share Based Compensation Award Tranche Four [Member]
Award Type
Award Type [Axis]
Equity Award
Share Based Compensation Arrangements By Share Based Payment Award Award Type And Plan Name [Domain]
Restricted common stock.
Restricted Common Stock [Member]
Restricted Common Stock [Member]
Warrant [Member]
Warrant [Member]
Antidilutive Securities
Antidilutive Securities Excluded From Computation Of Earnings Per Share By Antidilutive Securities [Axis]
Antidilutive Securities, Name
Antidilutive Securities Name [Domain]
Unvested restricted ordinary shares.
Unvested Restricted Ordinary Shares [Member]
Unvested Restricted Ordinary Shares [Member]
Exercise of Share Options and Subject to Future Vesting [Member]
Employee Stock Option [Member]
Class Of Stock [Line Items]
Class Of Stock [Line Items]
Stock conversion ratio
Conversion Of Stock Conversion Ratio
Stock issued during period shares subject to repurchase option.
Share based compensation arrangement by share based payment award option repurchase period from termination date.
Number of milestones achieved.
Unvested restricted stock shares.
Stock issued during period
Stock Issued During Period Shares New Issues
Share price of stock issued
Share Price
Shares subject to repurchase option
Stock Issued During Period Shares Subject To Repurchase Option
Share based compensation arrangement by share based payment award period from termination date of employee or consultant for repurchase of shares
Share Based Compensation Arrangement By Share Based Payment Award Option Repurchase Period From Termination Date
Shares vesting percentage
Number of milestones achieved
Number Of Milestones Achieved
Common shares, unvested
Unvested Restricted Stock Shares
Accelerated ordinary shares vested
Sharebased Compensation Arrangement By Sharebased Payment Award Accelerated Vesting Number
Modification expense resulting from accelerated vesting of ordinary shares
Share Based Compensation Arrangement By Share Based Payment Award Accelerated Compensation Cost
Shares issued upon warrant conversion.
Warrant outstanding
Class Of Warrant Or Right Outstanding
Common shares issued upon warrant conversion
Shares Issued Upon Warrant Conversion
Proceeds from warrant exercised
Proceeds From Issuance Of Warrants
Antidilutive securities excluded from computation of earnings per share
Antidilutive Securities Excluded From Computation Of Earnings Per Share Amount
Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table]
Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table]
Plan Name
Plan Name [Axis]
Plan Name
Plan Name [Domain]
Two thousand thirteen equity incentive plan.
2013 Equity Incentive Plan [Member]
Two Thousand Thirteen Equity Incentive Plan [Member]
Stock Option [Member]
Two thousand ten equity incentive plan.
2010 Equity Incentive Plan [Member]
Two Thousand Ten Equity Incentive Plan [Member]
Two thousand eighteen omnibus inactive plan.
2018 Omnibus Equity Incentive Plan [Member]
Two Thousand Eighteen Omnibus Inactive Plan [Member]
Non executive officer.
Non-Executive Officer [Member]
Non Executive Officer [Member]
Income Statement Location
Income Statement Location [Axis]
Income Statement Location
Income Statement Location [Domain]
General and Administrative [Member]
General And Administrative Expense [Member]
Performance-based options.
Performance Based Options
Performance Based Options [Member]
Board of members.
Board of Members [Member]
Board Of Members [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Shares authorized for grant
Share Based Compensation Arrangement By Share Based Payment Award Number Of Shares Authorized
Common stock reserved for future issuance
Common Stock Capital Shares Reserved For Future Issuance
Reverse share split, description
Shares issued in period
Share Based Compensation Arrangement By Share Based Payment Award Shares Issued In Period
Expected life (in years)
Sharebased Compensation Arrangement By Sharebased Payment Award Fair Value Assumptions Expected Term1
Expected volatility
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Volatility Rate
Expected dividend yield
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Dividend Rate
Risk-free interest rate
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Risk Free Interest Rate
Grant date weighted average fair value
Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Weighted Average Grant Date Fair Value
Number of Shares, Outstanding
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Number
Number of Shares, Granted
Number of Shares, Exercised
Number of Shares, Forfeited/cancelled
Share Based Compensation Arrangement By Share Based Payment Award Options Forfeitures In Period
Number of Shares, Outstanding
Number of Shares, Exercisable – December 31, 2018
Share Based Compensation Arrangement By Share Based Payment Award Options Exercisable Number
Number of Shares, Exercisable and expected to vest – December 31, 2018
Share Based Compensation Arrangement By Share Based Payment Award Options Vested And Expected To Vest Exercisable Number
Weighted-Average Exercise Price, Outstanding
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Weighted Average Exercise Price
Weighted-Average Exercise Price, Granted
Share Based Compensation Arrangements By Share Based Payment Award Options Grants In Period Weighted Average Exercise Price
Weighted-Average Exercise Price, Exercised
Share Based Compensation Arrangements By Share Based Payment Award Options Exercises In Period Weighted Average Exercise Price
Weighted-Average Exercise Price, Forfeited/cancelled
Share Based Compensation Arrangements By Share Based Payment Award Options Forfeitures In Period Weighted Average Exercise Price
Weighted-Average Exercise Price, Outstanding – December 31, 2018
Weighted-Average Exercise Price, Exercisable – December 31, 2018
Share Based Compensation Arrangement By Share Based Payment Award Options Exercisable Weighted Average Exercise Price
Weighted-Average Remaining Contractual Term (Years), Exercisable and expected to vest – December 31, 2018
Share Based Compensation Arrangement By Share Based Payment Award Options Vested And Expected To Vest Exercisable Weighted Average Exercise Price
Weighted-Average Remaining Contractual Term (Years), Outstanding – December 31, 2018
Sharebased Compensation Arrangement By Sharebased Payment Award Options Outstanding Weighted Average Remaining Contractual Term2
Weighted-Average Remaining Contractual Term (Years), Exercisable – December 31, 2018
Sharebased Compensation Arrangement By Sharebased Payment Award Options Exercisable Weighted Average Remaining Contractual Term1
Weighted-Average Remaining Contractual Term (Years), Exercisable and expected to vest – December 31, 2018
Sharebased Compensation Arrangement By Sharebased Payment Award Options Vested And Expected To Vest Exercisable Weighted Average Remaining Contractual Term1
Aggregate Intrinsic Value, Exercised
Share Based Compensation Arrangement By Share Based Payment Award Options Exercises In Period Total Intrinsic Value
Aggregate Intrinsic Value, Outstanding – December 31, 2018
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Intrinsic Value
Aggregate Intrinsic Value, Exercisable – December 31, 2018
Sharebased Compensation Arrangement By Sharebased Payment Award Options Exercisable Intrinsic Value1
Aggregate Intrinsic Value, Exercisable and expected to vest – December 31, 2018
Share Based Compensation Arrangement By Share Based Payment Award Options Vested And Expected To Vest Exercisable Aggregate Intrinsic Value
Compensation cost not yet recognized
Employee Service Share Based Compensation Nonvested Awards Total Compensation Cost Not Yet Recognized
Weighted-average remaining service period
Employee Service Share Based Compensation Nonvested Awards Total Compensation Cost Not Yet Recognized Period For Recognition1
Fair value of options vested
Sharebased Compensation Arrangement By Sharebased Payment Award Options Vested In Period Fair Value1
Share-based compensation arrangement by share-based payment award, options, vested and expected to vest, exercisable, subject to repurchase conditions, number.
Exercisable and expected to vest options, subject to repuchase conditions
Share Based Compensation Arrangement By Share Based Payment Award Options Vested And Expected To Vest Exercisable Subject To Repurchase Conditions Number
Research and Development [Member]
Research And Development Expense [Member]
Share-based compensation expenses
Allocated Share Based Compensation Expense
Share based compensation expense
Number of board members.
Number of board members
Number Of Board Members
United States
Income Loss From Continuing Operations Before Income Taxes Domestic
Foreign
Income Loss From Continuing Operations Before Income Taxes Foreign
Total loss before income taxes
Income Loss From Continuing Operations Before Income Taxes Minority Interest And Income Loss From Equity Method Investments
Maximum percentage of likelihood of uncertain tax position recognized to be sustained.
Income taxes.
Income taxes.
Income Taxes [Table]
Income Taxes [Table]
United States [Member]
UNITED STATES
California [Member]
CALIFORNIA
Income Tax Authority
Income Tax Authority [Axis]
Income Tax Authority
Income Tax Authority [Domain]
Federal [Member]
Domestic Country [Member]
State [Member]
State And Local Jurisdiction [Member]
Foreign [Member]
Foreign Country [Member]
Alcobra incorporation and alcobra limited.
Alcobra Inc. and Alcobra Ltd. [Member]
Alcobra Incorporation And Alcobra Limited [Member]
Tax Credit Carryforward
Tax Credit Carryforward [Axis]
Tax Credit Carryforward, Name
Tax Credit Carryforward Name [Domain]
Research Tax Credit Carryforward [Member]
Research [Member]
Income Taxes [Line Items]
Income Taxes [Line Items]
Maximum percentage of likelihood of uncertain tax position recognized to be sustained
Maximum Percentage Of Likelihood Of Uncertain Tax Position Recognized To Be Sustained
Reconciliation Of Unrecognized Tax Benefits Excluding Amounts Pertaining To Examined Tax Returns Roll Forward
Beginning balance of unrecognized tax benefits
Unrecognized Tax Benefits
Settlement of prior period tax positions
Unrecognized Tax Benefits Decreases Resulting From Settlements With Taxing Authorities
Increase for prior period tax positions
Unrecognized Tax Benefits Increases Resulting From Prior Period Tax Positions
Increase for current period tax positions
Unrecognized Tax Benefits Increases Resulting From Current Period Tax Positions
Ending balance of unrecognized tax benefits
Unrecognized Tax Benefits
Unrecognized tax benefits impacting effective tax rate
Unrecognized Tax Benefits That Would Impact Effective Tax Rate
Unrecognized Tax Benefits, Income Tax Penalties and Interest Expense
Unrecognized Tax Benefits Income Tax Penalties And Interest Expense
Deferred tax assets property, plant and equipment and intangible assets.
Deferred tax assets property, plant and equipment and intangible assets.
Deferred tax assets:
Deferred Tax Assets Gross [Abstract]
Net operating loss
Deferred Tax Assets Operating Loss Carryforwards
Tax credits
Deferred Tax Assets Tax Credit Carryforwards
Accrued liabilities
Deferred Tax Assets Tax Deferred Expense Reserves And Accruals Accrued Liabilities
Deferred revenue
Deferred Tax Assets Deferred Income
Depreciation and amortization
Deferred Tax Assets Property Plant And Equipment And Intangible Assets
Share-based compensation
Deferred Tax Assets Tax Deferred Expense Compensation And Benefits Share Based Compensation Cost
Total gross deferred tax assets
Deferred Tax Assets Gross
Deferred tax liabilities:
Deferred Tax Liabilities [Abstract]
Depreciation and amortization
Deferred Tax Liabilities Property Plant And Equipment And Intangible Assets
Valuation allowance
Deferred Tax Assets Valuation Allowance
Net deferred tax asset
Deferred Tax Assets Liabilities Net
Operating loss carryforwards expiration year.
Operating Loss Carryforwards
Operating Loss Carryforwards
Operating Loss Carryforwards Expiration Year
Operating Loss Carryforwards Expiration Year
Net operating loss excluded from deferred tax assets.
Net operating loss amount excluded from deferred tax assets
Net Operating Loss Excluded From Deferred Tax Assets
Tax credit carryforward expiration year.
Credit Carryforward Amount
Tax Credit Carryforward Amount
Credit Carryforward Expiration Year
Tax Credit Carryforward Expiration Year
Research and Development Expenses
Net operating loss and research and development credit carryforwards limitations on cumulative change in ownership minimum percentage.
Net operating loss and research and development credit carryforwards limitations on cumulative change in ownership period.
Net Operating Loss and Research and Development Credit Carryforwards Limitations On Cumulative Change In Ownership Minimum Percentage
Net Operating Loss And Research And Development Credit Carryforwards Limitations On Cumulative Change In Ownership Minimum Percentage
Net Operating Loss and Research and Development Credit Carryforwards Limitations on Cumulative Change In Ownership Period
Net Operating Loss And Research And Development Credit Carryforwards Limitations On Cumulative Change In Ownership Period
Effective income tax rate reconciliation tax cuts and jobs act of 2017 Percent.
Federal statutory income tax rate
Effective Income Tax Rate Reconciliation At Federal Statutory Income Tax Rate
State income taxes, net of federal benefit
Effective Income Tax Rate Reconciliation State And Local Income Taxes
Foreign rate differential
Effective Income Tax Rate Reconciliation Foreign Income Tax Rate Differential
Share-based compensation
Effective Income Tax Rate Reconciliation Nondeductible Expense Share Based Compensation Cost
Tax Cuts and JOBS Act
Effective Income Tax Rate Reconciliation Tax Cuts And Jobs Act Of2017 Percent
Change in tax rate
Effective Income Tax Rate Reconciliation Change In Enacted Tax Rate
Change in valuation allowance
Effective Income Tax Rate Reconciliation Change In Deferred Tax Assets Valuation Allowance
Other
Effective Income Tax Rate Reconciliation Tax Credits Other
Permanent differences
Effective Income Tax Rate Reconciliation Other Adjustments
Provision for income taxes
Effective Income Tax Rate Continuing Operations
Federal statutory income tax rate
Amount of income tax expense (benefit) for measurement period adjustment from accounting for tax effect pursuant to Tax Cuts and Jobs Act.
Measurement period adjustment
Tax Cuts And Jobs Act Of2017 Measurement Period Adjustment Income Tax Expense Benefit
Amount of reasonable estimate for income tax expense (benefit) for remeasurement of deferred tax from change in tax rate pursuant to Tax Cuts and Jobs Act for which accounting for tax effect is incomplete.
Provisional amount offsetted by valuation allowance
Tax Cuts And Jobs Act Of2017 Incomplete Accounting Change In Tax Rate Provisional Income Tax Expense Benefit
Grants received.
Commitment and contingencies.
Commitment and contingencies.
Commitment And Contingencies [Table]
Commitment And Contingencies [Table]
Research and Development Arrangement, Contract to Perform for Others, Type
Research And Development Arrangement Contract To Perform For Others By Type [Axis]
Research and Development Arrangement, Contract to Perform for Others, Type
Research And Development Arrangement Contract To Perform For Others Type [Domain]
Cystic Fibrosis Foundation Therapeutics grants.
Cystic Fibrosis Foundation Therapeutics Grants [Member]
Cystic Fibrosis Foundation Therapeutics [Member]
San Diego, California.
San Diego, California [Member]
San Diego California [Member]
Lease Arrangement, Type
Lease Arrangement Type [Axis]
Lease Arrangement, Type
Lease Arrangement Type [Domain]
October 2017 lease amendment.
October 2017 Lease Amendment [Member]
October Two Thousand And Seventeen Lease Amendment [Member]
Commitment And Contingencies [Line Items]
Commitment And Contingencies [Line Items]
Grants received
Grants Received
Lessor leasing arrangements operating leases period year and month.
Operating lease expiration period year and month
Lessor Leasing Arrangements Operating Leases Expiration Period Year And Month
Lessor leasing arrangements operating leases extended lease.
Operating lease extended additional term
Lessor Operating Lease Renewal Term
Lessor, operating lease, term of contract
Lessor Operating Lease Term Of Contract
Tenant improvement allowance
Payments For Proceeds From Tenant Allowance
Lessor leasing arrangements operating leases extended lease
Lessor Leasing Arrangements Operating Leases Extended Lease
Security
Security Deposit
Operating lease rent expense
Operating Leases Rent Expense Net
2019
Operating Leases Future Minimum Payments Due Current
2020
Operating Leases Future Minimum Payments Due In Two Years
2021
Operating Leases Future Minimum Payments Due In Three Years
2022
Operating Leases Future Minimum Payments Due In Four Years
2023
Operating Leases Future Minimum Payments Due In Five Years
Thereafter
Operating Leases Future Minimum Payments Due Thereafter
Total
Operating Leases Future Minimum Payments Due
Schedule Of Related Party Transactions By Related Party [Table]
Schedule Of Related Party Transactions By Related Party [Table]
Research Collaboration and License Agreement [Member]
Related Party Transaction [Line Items]
Related Party Transaction [Line Items]
Accounts receivable, outstanding
Accounts Receivable Related Parties
Stock compensation expense recognized
Professional fees
Professional Fees